Effects of paralysis with pancuronium bromide on joint mobility in premature infants.

Fanconi, S; Ensner, S; Knecht, B · J Pediatr · 1995

case_control · Level III

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Abstract

To study the effects of muscle paralysis on joint mobility, we compared eight premature infants treated with pancuronium bromide with a control group. A significant reduction was observed in hip and knee flexion, and in ankle dorsal extension, which tended to resolve in time. We conclude that muscle paralysis reduces the mobility of selected joints; spontaneous activity appears to prevent long-term contractures.

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