Human herpesvirus-6 infection in children with first febrile seizures.
prospective_cohort · Level II
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Abstract
We evaluated febrile convulsions prospectively in 42 children to investigate the association between acute human herpesvirus-6 (HHV-6) infection and first-time febrile convulsions, using both virologic and serologic methods. Eight children had primary HHV-6 infection documented by viral culture and an additional three by acute- and convalescent-phase serologic studies. These findings indicate that acute HHV-6 infection is a frequent cause of febrile convulsions in young children.
Medical subject headings
- Exanthema Subitum
- Herpesvirus 6, Human
- Seizures, Febrile