Small intestinal carcinoma with osteoclast-like giant cells.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 7611227.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An elderly woman underwent jejunectomy for a large, stenosing neoplasm. Histologically, we found an undifferentiated carcinoma with scattered mononuclear and multinuclear macrophages in the intestine and lymph node metastases. The multinuclear cells, being acid phosphatase-positive and CD68-immunoreactive, are referred to as osteoclast-like giant cells. Hepatic secondaries were discovered 6 months postoperatively. The patient succumbed to a chemotherapy-related septic event. We suggest that intratumoral infiltration by mononuclear and multinuclear macrophages expresses one of the body's defense mechanisms against cancer.
Medical subject headings
- Carcinoma
- Giant Cells
- Jejunal Neoplasms
- Osteoclasts