Three-dimensional functional magnetic resonance imaging of human brain on a clinical 1.5-T scanner.
basic_science · Level V
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- Record sourced from PubMed, PMID 7624341.
- Also identified by PMC identifier 41439.
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Abstract
Functional magnetic resonance imaging (fMRI) is a tool for mapping brain function that utilizes neuronal activity-induced changes in blood oxygenation. An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware. This approach uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation. Motor stimulation, induced by self-paced finger tapping, reliably produced significant signal increase in the hand region of the contralateral primary motor cortex in every subject tested.
Medical subject headings
- Brain
- Magnetic Resonance Imaging
- Motor Activity
- Motor Cortex