Sclerochoroidal granuloma in Wegener's granulomatosis simulating a uveal melanoma.

Abstract

It is known that Wegener's granulomatosis may affect the eye, but macroscopically visible granulomas in patients with this condition have not yet been described. Results of clinical, ultrasound, and histologic examination of a patient with Wegener's granulomatosis are presented. A sclerochoroidal granuloma in this patient simulated an uveal melanoma. It was not possible to unequivocally differentiate the lesion from a uveal melanoma on sonographic examination, but histologic examination confirmed the diagnosis of sclerochoroidal granuloma. Macroscopically visible sclerochoroidal granuloma is another facet of Wegener's granulomatosis, and in some cases may be mistaken for uveal melanoma.