Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 7638812.
- Also identified by PMC identifier 1021270.
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Abstract
A statistical audit of adenosine deaminase (ADA) in pleural effusions was undertaken. ADA analysis, cytological and microbiological examinations, and differential cell counts were performed on 462 pleural fluid samples. ADA activity in tuberculous effusions was higher than in any other diagnostic group. At a level of 50 U/l the sensitivity and specificity for the identification of tuberculosis was 90% and 89%, respectively. ADA activity remains a useful test in the evaluation of pleural effusions.
Medical subject headings
- Adenosine Deaminase
- Clinical Enzyme Tests
- Pleural Effusion
- Tuberculosis, Pleural