The dominant class of somatosensory neurone recorded in the spinal dorsal horn of awake sheep has wide dynamic range properties.

Abstract

In order to investigate the properties of dorsal horn neurones in the absence of the distorting influences of anaesthesia, preparative surgery, prior training or excessive restraint, recordings have been made in sheep chronically prepared for single-cell recording. Within the limitations of sampling error of dorsal horn neurones with cutaneous receptive fields, the cell type most frequently encountered had wide dynamic range (WDR; convergent; multireceptive) properties; these accounted for 59% of the 46 neurones that were examined in detail. High-threshold mechanoreceptive (nocispecific) and low-threshold mechanoreceptive neurones formed 11% and 30% of the sample, respectively. These and other data indicate that under normal physiological conditions in the awake state, many spinal neurones do indeed have WDR properties, implying that these cells have an important function in nociceptive processing.