Frequency encoding in excitable systems with applications to calcium oscillations.
basic_science · Level V
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- Record sourced from PubMed, PMID 7644505.
- Also identified by PMC identifier 41247.
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Abstract
A number of excitable cell types respond to a constant hormonal stimulus with a periodic oscillation in intracellular calcium. The frequency of oscillation is often proportional to the hormonal stimulus, and one says that the stimulus is frequency encoded. Here we develop a theory of frequency encoding in excitable systems and apply it to intracellular calcium oscillations that results from increases in the intracellular level of inositol 1,4,5-triphosphate.
Medical subject headings
- Calcium
- Mathematics
- Models, Biological