The estimation of inspired isoflurane concentration in a low-flow system.

Gowrie-Mohan, S; Chakrabarti, M K; Lockwood, G G · Anaesthesia · 1995

prospective_cohort · Level II

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Abstract

We have examined the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system. Twenty one adult patients requiring mechanical ventilation of the lungs during surgery took part in this study. Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia. The ratio was maintained throughout the procedure, except for a few minutes following each change in vaporizer setting.

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