Leukotriene B4 as a marker of cerebral dysfunction.
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- Record sourced from PubMed, PMID 7653755.
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Abstract
It has been postulated that leukotriene B4 is involved in the pathogenesis of postischaemic cerebral oedema. We set out to determine if a relationship exists between jugular bulb leukotriene B4 and other indicators of cerebral ischaemia. No association could be demonstrated for either intracranial pressure, jugular bulb blood oxygen saturation or lactate oxygen index. Our results provide insufficient evidence to suggest that measurement of leukotriene B4 has any place in the management of head-injured patients.
Medical subject headings
- Brain Ischemia
- Craniocerebral Trauma
- Leukotriene B4