The anticonvulsant hypersensitivity syndrome.

Handfield-Jones, S E; Jenkins, R E; Whittaker, S J; Besse, C P; McGibbon, D H · Br J Dermatol · 1993

case_report · Level V

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Abstract

Anticonvulsants can cause a characteristic hypersensitivity reaction. This multisystem reaction typically presents as fever, mucocutaneous eruptions, lymphadenopathy and hepatitis. There is cross-reactivity between different anticonvulsants, which complicates subsequent therapy. We report three cases to illustrate both the typical features, and less common complications, of this under-recognized and life-threatening syndrome.

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