Symptomatic tumors affecting the urinary tract in children with neurofibromatosis.
case_series · Level IV
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Abstract
We determined the need for urological screening in children with neurofibromatosis. Of 96 children with neurofibromatosis treated at our institution 6 (6.2%) had a symptomatic tumor that affected the urinary tract. There were 5 plexiform neurofibromas and 1 prostatic rhabdomyosarcoma. Five children had a palpable abdominal mass and 3 required urinary diversion. Since most morbidity resulted because tumors were advanced by the time symptoms developed, we suggest that children with neurofibromatosis be screened annually with medical history, physical examination, urinalysis and serum chemistry studies for tumors that affect the urinary tract.
Medical subject headings
- Neurofibroma
- Neurofibromatosis 1
- Prostatic Neoplasms
- Rhabdomyosarcoma
- Urologic Neoplasms