Tyrosine phosphorylation accompanying the cellularization of the syncytial blastoderm of Drosophila.

Loncar, D; Singer, S J · Proc Natl Acad Sci U S A · 1995

basic_science · Level V

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Abstract

At an early stage in embryogenesis, the Drosophila blastoderm is a syncytium in which approximately 6000 nuclei align under the plasma membrane. During the interphase of nuclear cycle 14, a wave of membrane formation descends from the blastoderm surface to enclose each nucleus in an intact cell membrane. We show by immunofluorescence microscopy that the membrane-formation process is closely accompanied in space and time by a wave of tyrosine phosphorylation, suggesting that one or more tyrosine kinases and phosphatases are active in the process.

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