Successful outcome of progressive multifocal leukoencephalopathy with cytarabine and interferon.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 7683856.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The prognosis of patients with progressive multifocal leukoencephalopathy is poor, with few patients showing remission or surviving. We describe a 37-year-old man who developed progressive multifocal leukoencephalopathy in association with sarcoidosis. Despite treatment with cytarabine and acyclovir, he continued to deteriorate. Shortly following the addition of interferon alfa, he made a dramatic improvement, regaining full functional independence. The use of interferon alfa in addition to cytarabine in such patients offers a new therapeutic approach worthy of further trial.
Medical subject headings
- Cytarabine
- Interferons
- Leukoencephalopathy, Progressive Multifocal