Sequence-specific scission of DNA by RNAs linked to a chemical nuclease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 7684825.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
RNAs linked to the chemical nuclease 1,10-phenanthroline-copper cut double-stranded DNA of complementary sequence. This cleavage reaction is applicable to all sequences and can be used to measure the distance between marker genes in base pairs, map the size of a transcription unit and define positions of chromosomal breakpoints.
Medical subject headings
- Copper
- DNA
- Deoxyribonucleases
- Phenanthrolines
- RNA