Portal vein thrombosis caused by protein C and protein S deficiency associated with cytomegalovirus infection.

Arav-Boger, R; Reif, S; Bujanover, Y · J Pediatr · 1995

case_report · Level V

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Abstract

A 4-month-old girl who was examined because of splenomegaly had portal vein thrombosis, which apparently resulted from a combination of cytomegalovirus infection and deficiency of both protein S and protein C. The cytomegalovirus infection, by damaging endothelial cells, may have triggered a cascade of events that was ultimately expressed as portal vein thrombosis resulting from deficiency of proteins S and C.

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