Treatment of progressive outer retinal necrosis with sorivudine.
case_report · Level V
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Abstract
We examined a patient with progressive outer retinal necrosis, which is presumably caused by the varicella-zoster virus in patients with the acquired immunodeficiency syndrome. The patient was successfully treated with a combination of intravitreal ganciclovir and oral sorivudine. Treatment for progressive outer retinal necrosis has been disappointing; both acyclovir and ganciclovir have had only limited success. Sorivudine, a new antiviral medication with activity against varicella-zoster virus, may represent an effective alternative treatment for retinal necrosis.
Medical subject headings
- Antiviral Agents
- Arabinofuranosyluracil
- Retinal Necrosis Syndrome, Acute