Transient neonatal diabetes and later onset diabetes: a case of inherited insulin resistance.
case_report · Level V
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- Record sourced from PubMed, PMID 7717741.
- Also identified by PMC identifier 1510981.
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Abstract
A 13 year old girl who had had transient neonatal diabetes developed permanent diabetes. She had raised fasting insulin concentrations suggestive of insulin resistance with a suboptimal insulin response to glucose loading. Both her mother and sister had profound insulin resistance; neither had clinical diabetes. This is the first time inherited insulin resistance has been implicated in the pathogenesis of permanent diabetes developing after transient neonatal diabetes.
Medical subject headings
- Diabetes Mellitus, Type 1
- Insulin Resistance