Delayed hypersensitivity to one low-molecular-weight heparin with tolerance of other low-molecular-weight heparins.

Bircher, A J; Itin, P H; Tsakiris, D A; Surber, C · Br J Dermatol · 1995

case_report · Level V

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Abstract

We report a patient who developed infiltrated plaques at the sites of subcutaneous injection of a low-molecular-weight heparin. Skin tests and a lymphocyte transformation test revealed hypersensitivity to sandoparin and heparin sodium. The low-molecular-weight heparins nadroparin and dalteparin were subsequently tolerated without adverse effects. Possible risk factors for sensitization are discussed.

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