Methodological issues in the assessment of neuropsychologic function after cardiac surgery.

Blumenthal, J A; Mahanna, E P; Madden, D J; White, W D; Croughwell, N D; Newman, M F · Ann Thorac Surg · 1995

review · Level V

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Abstract

This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive decline; (6) statistical analysis; and (7) clinical significance. Implications for further research in the area are discussed.

Medical subject headings