Seasonal rhythm of platelet [3H]imipramine binding in adolescents who attempted suicide.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 7755125.
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Abstract
This study was designed to determine the seasonality of serotonin functions among adolescents who attempt suicide. Platelet [3H]imipramine binding was assessed over a period of 18 months in 98 adolescents who attempted suicide and a comparison group of 23 never-suicidal youths with conduct disorder. [3H]Imipramine (Bmax) was uncorrelated with age, but showed considerable seasonal variability over time in those who had attempted suicide. [3H]Imipramine binding density in adolescents who attempted suicide exhibited significant seasonality, reaching a nadir in late winter/early spring.
Medical subject headings
- Blood Platelets
- Imipramine
- Seasons
- Suicide, Attempted