Severe halogen acne due to a trifluoromethylpyrazole derivative and its resistance to isotretinoin.
case_report · Level V
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Abstract
We report a case of severe chloracne, with systemic involvement, following occupational exposure to dihydrotrifluoromethylphenyl benzothiopyranopyrazolone, which, to our knowledge, has not been previously reported as a cause of chloracne. Aggressive drug treatment, including high-dose oral isotretinoin was of limited benefit in suppressing the disease activity.
Medical subject headings
- Acne Vulgaris
- Drug Industry
- Hydrocarbons, Fluorinated
- Occupational Diseases
- Occupational Exposure
- Pyrazoles
- Pyrazolones