Incidence of penile pain after injection of a new formulation of prostaglandin E1.
case_control · Level III
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Abstract
We determined the incidence of pain with injection of a new formulation of prostaglandin E1. A total of 63 subjects with erectile dysfunction underwent treatment with the new formulation of prostaglandin E1. Evidence of pain associated with injection was obtained by questionnaire and through questioning. A total of 451 injections was given to 63 subjects in the office, with 16 episodes (3.5%) of pain in 10 (15.9%). Then, 680 injections were performed by 38 subjects at home, with 15 episodes (2.2%) of pain in 8 (21%). Pain was not dose related. The new formulation of prostaglandin E1 is less likely to be associated with pain compared with alcohol based formulations.
Medical subject headings
- Alprostadil
- Erectile Dysfunction
- Pain
- Penis