Cephalosporin-induced recurrent aseptic meningitis.

Creel, G B; Hurtt, M · Ann Neurol · 1995

case_report · Level V

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Abstract

A 66-year-old woman had several episodes of aseptic meningitis associated with exposure to cephalexin, cefazolin, and ceftazidime. The cerebrospinal fluid IgG index was elevated, specific IgG-ceftazidime binding was shown, and skin allergy testing with cefazolin provoked a recurrence of meningitis. We postulate an acute hypersensitivity reaction involving an antigen-specific humoral immune response.

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