Trigeminal neuralgia in multiple sclerosis relieved by a prostaglandin E analogue.

Reder, A T; Arnason, B G · Neurology · 1995

case_series · Level IV

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Abstract

Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy.

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