Gabapentin treatment of seizures in acute intermittent porphyria.
case_report · Level V
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Abstract
Most antiepileptic drugs (AEDs) available have demonstrated porphyrogenicity in hepatic porphyrias. Gabapentin is a new AED not appreciably metabolized by the liver in humans. We report two patients with acute intermittent porphyria successfully treated with gabapentin without its inducing porphyric crisis.
Medical subject headings
- Acetates
- Amines
- Cyclohexanecarboxylic Acids
- Epilepsy
- Porphyria, Acute Intermittent
- gamma-Aminobutyric Acid