Schizophrenic and manic brains in Nigerians. Computerised tomography findings.

Ohaeri, J U; Adeyinka, A O; Enyidah, S N; Osuntokun, B O · Br J Psychiatry · 1995

case_control · Level III

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Abstract

We highlight the profile of brain computerised tomography (CT) measures among Nigerian psychiatric patients for comparison with findings from developed countries, and study of the relationship between CT values and clinical variables. Seven brain ventricle measures of 50 schizophrenic patients, 14 manic patients, and 41 healthy control subjects were compared. Patients had a significantly higher mean Sylvian fissure area. The third ventricle of schizophrenic patients was significantly larger than those of control subjects. CT measures were not significantly correlated with duration of illness. The so-called functional psychotic states are most probably associated with non-specific brain abnormality.

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