Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation.
case_series · Level IV
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Abstract
Cytogenetic investigation of endometrial polyps revealed the presence of a t(6;14)(p21;q24) as the sole abnormality in three cases. All tumors showed a histopathological pattern of predominant stromal hyperplasia with scarce representation of glandular elements, suggesting that a cytogenetic subgroup characterized by the t(6;14) translocation can be associated with endometrial polyps with a preponderant component of mesenchymal origin.
Medical subject headings
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 6
- Endometrial Neoplasms
- Polyps
- Translocation, Genetic