Simultaneous onset of Vogt-Koyanagi-Harada syndrome in monozygotic twins.
case_report · Level V
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- Record sourced from PubMed, PMID 7832237.
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Abstract
We examined monozygotic twins of Vietnamese ancestry in whom the Vogt-Koyanagi-Harada syndrome developed. Both patients demonstrated typical clinical findings of the Vogt-Koyanagi-Harada syndrome, and HLA typing disclosed HLA-DR4, an antigen that is present in a disproportionate number of patients with the Vogt-Koyanagi-Harada syndrome. Although familial cases of the Vogt-Koyanagi-Harada syndrome are rare, associations with HLA antigens may indicate that genetic factors play a role in this disease.
Medical subject headings
- Diseases in Twins
- Twins, Monozygotic
- Uveomeningoencephalitic Syndrome