Heparin-induced thrombocytopenia and heart operation: management with tedelparin.
case_report · Level V
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Abstract
Anticoagulation for cardiopulmonary bypass in the infrequent clinical setting of thrombocytopenia associated with the use of unfractionated heparin is a very serious problem. We describe a case in which a low-molecular-weight heparin (tedelparin) was selected for this purpose based on a platelet aggregation test, permitting adequate anticoagulation during cardiopulmonary bypass for valve replacement. This case report might help establish an adequate anticoagulation protocol when faced with a patient suffering from this condition.
Medical subject headings
- Cardiopulmonary Bypass
- Dalteparin
- Heparin
- Platelet Aggregation Inhibitors
- Thrombocytopenia