High CTG repeat number in nodular thyroid tissue from a myotonic dystrophy patient.
case_report · Level V
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- Record sourced from PubMed, PMID 7853378.
- Also identified by PMC identifier 1016667.
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Abstract
CTG triplet expansion was studied in lymphocytes and thyroid tissue in a patient with myotonic dystrophy (DM) and associated thyroid nodular disease. An approximately 7 fold larger amplification was found in abnormal thyroid tissue compared to lymphocytes, suggesting that anomalies in the putative DM kinase gene might contribute to thyroid dysfunction.
Medical subject headings
- Myotonic Dystrophy
- Repetitive Sequences, Nucleic Acid
- Thyroid Gland