MR measurements of mesenteric venous flow: prospective evaluation in healthy volunteers and patients with suspected chronic mesenteric ischemia.

Abstract

To quantify portal vein (PV) and superior mesenteric vein (SMV) flow before and after a standardized meal in healthy volunteers and to prospectively evaluate patients with a clinical suspicion of chronic mesenteric ischemia on the basis of magnetic resonance (MR) measurement of flow in the mesenteric venous system in volunteers. Cine phase-contrast flow measurements were acquired in 10 asymptomatic volunteers and in 10 patients. In volunteers, the difference between the fasting and post-prandial flows in the SMV and PV was significant (P < .001), with a peak flow augmentation of 245% +/- 74 and 70% +/- 29, respectively. Postprandial augmentation of peak flow in the SMV was significantly less in patients with mesenteric ischemia compared with volunteers (64% +/- 28; P = .02). SMV flow augmentation in patients without mesenteric ischemia did not differ significantly from that in volunteers (206% +/- 36; P = .31). Measurement of postprandial flow augmentation in the SMV with MR imaging shows promise as a noninvasive screening test for chronic mesenteric ischemia.