Neuroleptic exposure following inpatient treatment of acute mania with lithium and neuroleptic.

Sernyak, M J; Griffin, R A; Johnson, R M; Pearsall, H R; Wexler, B E; Woods, S W · Am J Psychiatry · 1994

retrospective_cohort · Level III

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Abstract

The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they were receiving a mean of 634 mg/day (SD = 684). This decrease was statistically significant, but the patients' ongoing neuroleptic exposure remained substantial.

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