Disseminated active HHV-6 infections in patients with AIDS.
case_series · Level IV
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- Record sourced from PubMed, PMID 7906332.
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Abstract
Human herpesvirus 6 (HHV-6) infected cells were detected in all lung, lymph-node, spleen, liver, and kidney tissues obtained at necropsy from an unselected series of nine patients with AIDS. This infection rate was significantly higher than that for cytomegalovirus. Lung infection with HHV-6 was extensive enough in one patient to account for fatal pneumonitis. In other tissues increased numbers of HHV-6 infected cells were related to the presence of lymphocytes infiltrates or residual lymphoid tissue, with lymphocytes being predominantly infected. Thus HHV-6 is an important pathogen in patients with AIDS.
Medical subject headings
- AIDS-Related Opportunistic Infections
- Acquired Immunodeficiency Syndrome
- Herpesviridae Infections
- Herpesvirus 6, Human