Small virus-like structure in fractions from scrapie hamster brain.
basic_science · Level V
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- Record sourced from PubMed, PMID 7908360.
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Abstract
The scrapie model in hamsters has been used to search for the agents that cause Creutzfeldt-Jakob disease in man and similar transmissible encephalopathies in animals. We found structures that are extraordinarily small for a virus, but exhibit viral structural properties in negatively stained samples, by electron microscopy in fractions containing scrapie-associated fibrils.
Medical subject headings
- Brain
- Scrapie