Sudden hearing loss associated with interferon.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 7910234.
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Abstract
With the increasing long-term use of interferon, several new adverse effects have been recognised. We have prospectively assessed auditory function in 49 patients receiving interferon, after we saw a case of sudden sensorineural hearing loss during interferon therapy. Auditory disability (tinnitus, hearing loss, or both) occurred in 22 patients (45%) during treatment with audiometry-documented sensorineural hearing loss in 18 (37%). The auditory disability often developed in the late stage of treatment and resolved in all patients within 7-14 days after discontinuation of interferon.
Medical subject headings
- Hearing Loss, Sensorineural
- Hepatitis B
- Interferon-alpha
- Interferon-beta
- Tinnitus