Bilateral acetylsulfapyridine nephrolithiasis associated with chronic sulfasalazine therapy.
case_report · Level V
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Abstract
We report on formation of bilateral renal calculi secondary to sulfasalazine therapy for juvenile rheumatoid arthritis. The condition was successfully treated with extracorporeal shock wave lithotripsy. Analysis of the fragments with thin layer chromatography and nuclear magnetic resonance revealed acetylsulfapyridine, a metabolite of sulfasalazine.
Medical subject headings
- Kidney Calculi
- Sulfasalazine