Porphyria cutanea tarda: pregnancy versus estrogen effect.
case_report · Level V
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- Record sourced from PubMed, PMID 7913477.
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Abstract
We describe the worsening of porphyria cutanea tarda in a young woman while she was taking oral contraceptives. However, she did not have an exacerbation during two pregnancies. We conclude that estrogens produced during pregnancy do not exert the same effect as orally administered medications that contain estrogen. The pronounced effect of oral ethinyl estradiol on the liver may be attributed to its first-pass effect on that organ.
Medical subject headings
- Contraceptives, Oral, Synthetic
- Mestranol
- Norethindrone
- Porphyria Cutanea Tarda
- Pregnancy Complications