Neurological examination abnormalities in neuroleptic-naive patients with first-break schizophrenia: preliminary results.

Sanders, R D; Keshavan, M S; Schooler, N R · Am J Psychiatry · 1994

prospective_cohort · Level II

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Abstract

The authors report preliminary findings from an ongoing prospective study of neuroleptic-naive patients with first-break schizophrenia. They evaluated 17 of these patients and 15 normal subjects with a structured neurological examination before the patients received any medical treatment. The patients with schizophrenia showed significantly greater neurological impairment than did the normal comparison subjects.

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