End-tidal partial pressure of carbon dioxide does not accurately reflect PaCO2 in rabbits treated with acetazolamide during anaesthesia.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 7917740.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Acetazolamide, a carbonic anhydrase inhibitor, may cause significant disturbances in carbon dioxide transport and elimination. In this study, end-tidal carbon dioxide monitoring has been used to study the correlation between arterial carbon dioxide (PaCO2) and end-tidal carbon dioxide partial pressure (PE'CO2) in rabbits treated with acetazolamide. A significant difference in (PaCO2-PE'CO2) developed immediately after administration of acetazolamide and persisted for more than 2 h. It is concluded that PE'CO2 did not reflect accurately PaCO2 and the ventilatory status of the rabbit which received acetazolamide within 2 h.
Medical subject headings
- Acetazolamide
- Anesthesia, General
- Carbon Dioxide
- Pulmonary Gas Exchange