Alanine at position 73 of HLA-C is associated with psoriasis vulgaris in Finland.
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- Record sourced from PubMed, PMID 7917991.
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Abstract
A close association was found between a specific sequence of HLA-C and psoriasis vulgaris in Finnish patients (chi 2 = 18.4, P = 1.78 x 10(-5)). This sequence codes for alanine at position 73 of the HLA-C molecule in the antigen binding cleft, and alanine may play a role in susceptibility to the disease.
Medical subject headings
- Alanine
- HLA-C Antigens
- Psoriasis