Sarcoid reactions in cystic duct carcinoma.

Klein, M; Kaminsky, P; Deibener, J; Cocciale, M P; Duc, M · Chest · 1994

case_report · Level V

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Abstract

A diagnosis of sarcoidosis was evoked in a 61-year-old man on clinical and histologic bases. Nevertheless, a bile duct carcinoma was disclosed in association with the discovery of generalized sarcoid-like granulomas. This is only the third time that such an association has been described. HLA-B8, DR3, and DRw52 antigens were found, suggesting that altered immunologic mechanisms could play a role in the pathogenesis of this sarcoid-like reaction.

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