Response of immunocompromised children with solid tumors to a conjugate vaccine for Haemophilus influenzae type b.

Shenep, J L; Feldman, S; Gigliotti, F; Roberson, P K; Marina, N; Foreschle, J E; Fullen, G H; Lott, L et al. · J Pediatr · 1994

prospective_cohort · Level II

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Abstract

Serum antibody response to a conjugated Haemophilus influenzae type b polyribosylribitol phosphate-diphtheria toxoid vaccine was assessed in nonvaccinated children aged 1 1/2 to 5 years receiving chemotherapy for solid tumors. Responses occurred in 21 (42%) of 50 children after first vaccination, and in 10 (45%) of 22 revaccinated children.

Medical subject headings