Levodopa failure in chronic manganism.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 7936281.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report a placebo-controlled study of levodopa in four patients with extrapyramidal deficits caused by chronic manganese intoxication. Their parkinsonism and dystonia had progressed slowly over a period of 5 years after they left the site of exposure. Initially the patients appeared to respond to levodopa in open observations, but this apparent benefit was not sustained. This short-term, double-blind study indicates that their parkinsonism and dystonia failed to respond to levodopa.
Medical subject headings
- Levodopa
- Manganese Poisoning
- Movement Disorders
- Nervous System Diseases