Triage methodology for the evaluation of implant-bone interfaces.

Abstract

Stainless steel plugs coated with and without Al2O3, TiO2 and Nb2O5 were inserted into canine femora in order to develop a methodology of rapid identification of appropriate specimens for deeper analysis of implant-bone interfaces. This approach is especially meaningful in areas where research funds are scarce. After a maximum follow-up period of 52 wk, bone segments containing plugs were radiographed using conventional techniques, high resolution techniques (which allowed a good preliminary evaluation) and microradiography. Analysis by X-ray fluorescence spectrometry indicated release of the materials by the implants. Microdensitometry of the microradiographs allowed a precise thickness determination of the tissue formed around the implants.