Granulomatous pneumonitis following intravesical BCG. What therapy is needed?
case_report · Level V
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- Record sourced from PubMed, PMID 7956439.
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Abstract
A 68-year-old man developed fever, cough, and dyspnea after intravesical bacillus Calmette-Guerin (BCG). Chest radiograph revealed diffuse reticulonodular infiltrates with caseating granulomas on transbronchial biopsy specimen. Cultures were negative and the patient's condition improved with corticosteroids. The mechanism for BCG-induced granulomatous inflammation is poorly understood. Optimal therapy includes corticosteroids.
Medical subject headings
- BCG Vaccine
- Granuloma
- Pneumonia