Immunology and disease control: a systems approach.

Asachenkov, A L; Marchuk, G I; Mohler, R R; Zuev, S M · IEEE Trans Biomed Eng · 1994

review · Level V

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Abstract

The application of system theory (or more precisely, differential equations) to immunology and disease, in general, is presented here. Particular results from U.S.-Russian research collaboration depict the potential role of such systematic analysis for more effective health care and disease control. In particular, some emphasis is given to control of influenza. After a brief systematic overview of immunology, a simple infectious disease model is developed to explain four basic forms of disease: subclinical, acute, lethal and chronic. Then, disease treatment is studied.

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