Subacute cor pulmonale due to microscopic pulmonary tumour cell embolization.

Lambert-Jensen, P; Mertz, H; Nyvad, O; Christensen, J H · J Intern Med · 1994

case_report · Level V

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Abstract

A case of a clinically occult ovarian carcinoma leading to subacute cor pulmonale in a 62-year-old woman is described. The patient was admitted to hospital with increasing respiratory distress. Physical examination and echocardiography showed signs of pulmonary hypertension. She died from circulatory failure. Autopsy revealed a bilateral ovarian carcinoma with diffuse carcinosis of the peritoneum. No gross evidence of pulmonary embolism was present, but microscopic investigation revealed tumour-related microangiopathic lesions causing the lethal pulmonary hypertension.

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