SecA homolog in protein transport within chloroplasts: evidence for endosymbiont-derived sorting.

Yuan, J; Henry, R; McCaffery, M; Cline, K · Science · 1994

basic_science · Level V

Where this comes from

Abstract

The SecA protein is an essential, azide-sensitive component of the bacterial protein translocation machinery. A SecA protein homolog (CPSecA) now identified in pea chloroplasts was purified to homogeneity. CPSecA supported protein transport into thylakoids, the chloroplast internal membrane network, in an azide-sensitive fashion. Only one of three pathways for protein transport into thylakoids uses the CPSecA mechanism. The use of a bacteria-homologous mechanism in intrachloroplast protein transport provides evidence for conservative sorting of proteins within chloroplasts.

Medical subject headings