Absence of Mycobacterium tuberculosis DNA in synovial fluid from patients with rheumatoid arthritis.
case_control · Level III
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- Record sourced from PubMed, PMID 7979585.
- Also identified by PMC identifier 1005439.
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Abstract
To determine whether Mycobacterium tuberculosis DNA can be detected in synovial fluid of patients with rheumatoid arthritis (RA). The polymerase chain reaction was applied to cellular components of synovial fluid. No evidence of M tuberculosis DNA was found in synovial fluid from 31 patients with RA and 13 control patients. The findings do not support a role for persistent M tuberculosis infection in the pathogenesis of RA.
Medical subject headings
- Arthritis, Rheumatoid
- DNA, Bacterial
- Mycobacterium tuberculosis
- Synovial Fluid